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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c235a2d33da5eaf985293fbccb63e0afa42b793d613dc8d5a24cf1bed60120e1' 
  AND token = 'mtGjnHR+dzFjYHJSwL45S5NLo5HeRA+GgqJa2tRfE1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}