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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5189b6485c35850137c40a5254e0f077decb125d3e680f5dc7cafc79e9c71b76' 
  AND token = 'z7HF5CB05TX9B0pRsoZUnp3FE59HCGddfJSdlIppx4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}