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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '587b1f7524590e444652b206c6e671dd952d24177ecbb5b9e5d64728e1bcb704' 
  AND token = '2JRBDxIRnsdfUxM0oqbsDBmXtFSrwJ9YH0rwHBEK0sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}