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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5aa1735de3269b0af540444f5935b1b566d2889405c6b8c75ad20f6985bf2e9' 
  AND token = 'JMqlJ6a5cBqqdM3d0Eq1C0ANZtFRiQjSLOh7wehoM4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}