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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fbe72d77c8529d5b63766b311dc280777ad9533fff25732260b82c020653368' 
  AND token = 'qahA4qSJ0ZvgWNYnvZCKN0t+sqzLM9cueydw2/TiFfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}