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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279942db5140ed73c6c697d0707465486efd52ed6c3f3033d4c96b6b3a646594' 
  AND token = 'pliQXsACgKQL3B2HUA4LmgrrLudwnKgU4TVwPWKHq84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}