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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca9ccf4c5fa244330136395a05864119a5bc8237df6f87e31c409140dacb3104' 
  AND token = 'Fa9h/NM52wlsJw+xcuEFS1fvkPbih6rf1khrc0dfQe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}