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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a7aeb2ce9b1a92b46b396baae3e181c2d9f856c953ccdd1e05cff2e6e95373f' 
  AND token = 'qPEFqW/yu5VWTv+Qc1BT5zmektXhP9OirHluZtvYhf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}