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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743602b409773bffa4d3c26952ab0a0c3bf293e0f6757aa4c4d7e37e2c4d522a' 
  AND token = 'PXpWa7tWaXfJ+FaD6fueBwezjHj8Jm8YN96FyJycR0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}