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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c5226308d5f86580c384e6b56ae8516c8e68c3ef92086dfdcd04d20ccd21a3' 
  AND token = 'hozu0x21RgvNkEOhZR7/GFRP+X5xqWF+IAmNOIZ0z/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}