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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e816da774872b503c2245e38141a90d1da0817e28d626ad81f55e12ff84212' 
  AND token = 'KgWcgubfjsK4sGh4ndRcUDkQnPKeSrkHLDgFiHVk2DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}