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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7fb56c987d52298a428263e15321f1d3fb7c79bb3322ade46ebcacb0e39a83a' 
  AND token = 'fEumcS9jkENWdLh/LNF/B6wTBpgzc+Db+eJsNLTlpRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}