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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b992106d02f5a63952d62a4289e371e32dc3d74839e13aea0d39d71ad979b26f' 
  AND token = 'M1icEe+137xDGQUsi3/Ji782jEwwnQxwukpscHdK2sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}