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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8eec87e1ba3a16456886bf20b11d9eddbd51be328e51ed3d79a1e095fdc9ce8' 
  AND token = 'y8geH8OqV0pIcWSY/BGN8KyCtKYssVrYOBxXsNSHzBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}