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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38db1fc79be7cd75e892bb8ec8da8b05a782b277ef454396f065c0f194f9773a' 
  AND token = '8k7hqKOHm0175cUK2SCYuVTSd0DXOwWQ9Z+3PPdjj9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}