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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5b537b34f4d3bc868b1593cb47f20ddab8d754afc32ec1febf5a215cd8a7b0' 
  AND token = 'e9D2pzuKGCFT3PQ5KkPzEqG1JQHFn2irTvE9ImoFKIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}