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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e252361cd94994940576c033eac1171f5996b6f46b021db2d311f845f37f60f5' 
  AND token = 'znrWOuCuKkrOZ6mEpfPtv7AzhOIHY09uO6GwC6DRVZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}