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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7deea931a7e14255d5ba017e281bfa1235d409a628d5b226d831312b546306' 
  AND token = 'S5UgnLiMXdlGB94+w+yby1GoncHPiAOoKJ71Ldl70KU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}