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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4efb8f519fc15f6e99b5b21cee9afc799e3a9855945e8cae2fc4d701c0150fd' 
  AND token = '+QPIo88o5nvJEAtGlFHRHNeVjEoe63xn0IwPhWZIXC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}