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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3180da659b8264b250160dd2eebe7731c140b327fb77b2c37e7db4c5df8bcd' 
  AND token = 'sD73kLjkp5zJ7iAZhFqfKbZiK54+Gebg8PimLmMd3i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}