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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481187102983314e59e5619001429aa2027a87b41dd0084ba314987d2c4983bb' 
  AND token = 'DB4gtDs70ARiLrW+IIe27AOmur8ZUl9FgVxWP1g5jhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}