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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f271ba398dc39e25ea79bbf15236980061b4a5244fc16b458522672592721ad' 
  AND token = 'Oj2RXnNa4N2q7g2rG2AS8uO2CIzkAzzyGbSxDP2klC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}