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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7ad6dfd937c49e49733099944f589695f76abc5bd5f799b67690abf5f0e6bc' 
  AND token = 'b8mXnqNILmcdO+2qS6v8xYy7F3HGz5jsTLLiU0S5zAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}