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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69c0da576171360b9b81adb0968dc7c9e524775f1d066085d7a0f8014d3cf0d4' 
  AND token = 'aMRR4ks8kiTIgPAzbPqjMbtwhWxru6EaeHmXpdSjTzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}