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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c518b037ed412a6cbcc3a0c275716b4c54a467a237a053f2d5a3c7c17a25c410' 
  AND token = 'fUKlmdFXXyKFBq7nsMWKPzi6k/rPm7bH9Imbx6R8V98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}