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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0f764ef8925843a3eb1a4d4084b3abb427009540971c7664702339c3b25fbd' 
  AND token = 'CNTEa8qb1R0QmfeuMzqR9YTnNQZST8DxWaAakAzGSmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}