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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25df1943002e8b2463b48a6293291d9df0ed42d8a14d856c365af5c82e36d72' 
  AND token = 'Of4X7Xy4oDvJIsebur9vV/2sXCtK9460azVdvoVMAcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}