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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4818a23dd44c99dedd8237f459fcae96c3a9794e62ed4c597fc8e75204116682' 
  AND token = '/Y7YhN7Gf0fqFBp11b0aEMqpXLcjDYi071Mpr6KvkRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}