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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca4adf8a66e23c01119d95a802bed888d97ffeff447e783b4a92e208aa351a7a' 
  AND token = 'DiaWqwC4CB8i4eISaGOkpfX8XWpJ+7JnBRvhWbia75Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}