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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc5e7e9e6b3d6ee6907b9e22252bdade998be783cddc3c24a12b53bbbe0093d8' 
  AND token = '7EGWQEwhNFqc6v/ejKaEJxu6GJjr5JUycjeZ71pE7uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}