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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17a5b6be6a96f6a163ceeaf24dab4a3ef55726a40ca001ddd1234a9d970f3ad6' 
  AND token = '/Zmd9QFO9YGd+c/MYZmnb0VKzX2hst2nqcOeuuPbuak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}