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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5660e3a9a94422bb683dea7e38f230db106c00d4f917829e0b22c4949a5a2f3e' 
  AND token = 'G5gg8TiUuppt4oSk52KeZ44JsxyuauIM1JTvXUo4JuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}