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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165fd7f88f03dbdad0da4a615113ed9dd4f0a1b2c2ab49cc9e6005d4410474e1' 
  AND token = 'OkEAXGq3NviNjqIlxIHGbUkOujYN02bSiD1h9I+TrKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}