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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075de238f8c0550523d4997713ac506a88c2a42665595eee7d3e3eb0eb5361aa' 
  AND token = 'pB4/KGpRZVvtOx+V6CRXhbu68BMhMWPancSpzgN81f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}