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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de8b66a388d0df21b1e52eeb33f57e6cebc63511ea83b573e7f2a715dcf88d3' 
  AND token = 'bcv9vzvXVsI6JDvJz+8O9RjsWLfFOiQMEzSnWQfzpCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}