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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27bc74e1e0ae239dfbd9660fc1cba0f31383d6788e37f4b07e7bbd4010763653' 
  AND token = '+ENfEWU4EDjMn5bzG9iDlUuTp/h363iOUdIoDdQqsBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}