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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e8e73fe5b355efd4a069a332f0bcda3e0626ca217f8f38f840e1b277aa6a2f0' 
  AND token = 'vgDs1QZH4oU/eJNvXmuGorOLhz5QApWYM0weRbIfM6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}