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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8efab659ce941050ba2817723d3edd1fc4ffc6213c78e7e686e60f55265c70c' 
  AND token = 's2xLhwZuoMU41+xWh0yMf1d1y9RI9T1sYkwBYIUqNSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}