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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3acad50b34bf4e18d93a54d1e0c114cf49dad15b93f383c579b763bb7de36f' 
  AND token = '16rTk/Od2LGd9y/g9dij54DZww1sEbabtriKmInnVaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}