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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b58146bbd7b72c5b367e5eab8525f1cbdcbbdff6d834980ef8afc4dc1e471329' 
  AND token = 'v6Sr6gZ52okfB0HBXOUKa2BzZUHcE4K0ydM7Ihm50U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}