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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59f719f395aa512959540c452047857c19586dc216a903d7e95ece9efc2b1639' 
  AND token = 'DWXiw/gCEDvPkSz5Mpzh0fEC5Y+vNIt1RzrmKE7ZoEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}