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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77160ff73b61f3bada611728d16235496521049220903a572a414c6743a8ca09' 
  AND token = '/oBbAkx9wp82xOc9LwjpY/oqxlWByKlV8e0WqNj9KMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}