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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27228d4ac28e0ab10438e7fe79f440b2b4bc0cad04c918f832930ba0ea757d5a' 
  AND token = 'h5XD3iFgjkJ6CpwzuXGFmOiAxRccefYk6o+9vzEUIhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}