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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6be0bd90faaf3b71309e8a1cbc11feb62ad56a4d4158c1d5dc01d1d6692f27fb' 
  AND token = 'mbJAwnD+rWxTrMCWw5vg2a0g2smInIKbgdxdBPfn9Go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}