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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5290d1a7a95fa1e2dc5d0424d39d8d07d8cbb1a93a6c70f4353c0bfa28442b02' 
  AND token = 'etGOCDuI8P/G5nTKqyanSwN6cKTA4/QIXnlpWmHh1gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}