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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19927719bf2f635eebbec7e7a23cacb6ab90c1f278e089a115e33fb1f629cb8f' 
  AND token = '+1VIWuEhtXhZ1OTlYd/dtiV55WqyT1fKq5egsgR+4Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}