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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed93bd03c1ec102ae7460afb59f2177310d9cf118c32c04f034748184affc989' 
  AND token = '5EA19PjnikOHn0J2+BFM78KTU6x7T25EqFtuVYi16sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}