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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e0254767a33b764a89994916f8a4ee1de6501e141f23403b38c7db1f7b0891' 
  AND token = 'A/JVjohv611puSIPScdIXgaZyvR1T9AD91yknE0slnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}