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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45eea25d9784dc38802b18fc7f027e9fe22550c6cc8e01129c59b3436934a09b' 
  AND token = 'Y4vhtW0igoXFl7SYdM6gefXLol9XqB5sj3pYIIZdEHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}