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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd93bcbd4b3df5beda8f9e12e5a10e230c90c704db1e59c8cf3423b646e42128' 
  AND token = 'r8aPYoLRixWqW8Om/HM44wEqEA4gZ+dj8qXoYOzgI2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}